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11th January -24
You have often prescribed Medicene
for my wife, which has relievd her pretty
much, I make no Doubt you well remember
what the Medicene consits of, as it has
been so Often applied for, respecting her
Costiveness of body, I will thank you
to send [by the bearer] about the same Quantity as you have
heretofore- by reference to yr. books you
can ascertain the Quantity - and instruction
how to mix it -I am yr. ObtTho: Barbour
Orange County