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26 May 1821
Dr
Since my bowels is no
better than when you saw
me I have some days 15
or 20 pases during the day
and nights I have very
little rest untill I take
a pill and then I can rest
nearly half the day and
after then Constant to
the pot then the same
Case at night untill I
take a pill in the morning
to day I took a pill about
12 O Clock. I wish you to
let me no whether or
not it will hurt me
by taking 3 pills a day
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my apetite is very bad
I Cannot eat any thing
pertickler of an evening
when I go so often to the
pot if these pills does
hurt me by takeing three
of them a day I wish you
Could send me some thing
that will Check it
in the same manner
I do not think there
Comes as mutch filth
w [h] at Comes is of a motlee
tuff nater somewhat
like snot with some
little blood I am y. st
James Holliday
To Drt Carmicheal
by george